GLP-1 Cost Guide 2026: Wegovy, Zepbound & Semaglutide Prices

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Quick answer: Without insurance, brand-name GLP-1s now cost $149–$449 a month self-pay: the Wegovy pill and Foundayo start at $149, Zepbound at $299 and the Wegovy pen at $349. Local clinic programs we checked in 13 metro areas posted semaglutide at a median of $299 a month and tirzepatide at $400. On Medicare, eligible patients pay $50 through the GLP-1 Bridge.

Brand-name self-pay prices (national)

Medication Self-pay price Where
Wegovy pill (oral semaglutide) $149/mo (1.5 mg); about $199–$299/mo for higher doses NovoCare Pharmacy, pharmacies
Wegovy pen (semaglutide) $199 for each of the first two fills (0.25 & 0.5 mg, new patients, through Dec 31, 2026), then $349/mo; Wegovy HD 7.2 mg $399/mo NovoCare Pharmacy
Zepbound (tirzepatide) $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg with on-time refills) LillyDirect
Foundayo (orforglipron pill) $149/mo (0.8 & 2.5 mg), $199 (5.5 mg), $299 (9–17.2 mg with on-time refills) LillyDirect
Medicare GLP-1 Bridge $50 per fill for eligible Part D enrollees (July 2026–Dec 2027) Medicare guide

Manufacturer self-pay prices as published by Novo Nordisk (NovoCare) and Eli Lilly (LillyDirect), checked October 27, 2026. Prices require a prescription and can change; some are limited-time offers.

Local clinic prices by metro area

Metro area Semaglutide (posted, monthly) Tirzepatide (posted, monthly) Clinics with prices
New York City $349–$700/mo $499–$750/mo 8
Los Angeles $99–$800/mo $299–$925/mo 8
Chicago $150–$350/mo $225–$409/mo 6
Dallas–Fort Worth $299/mo $425–$499/mo 4
Houston $299–$400/mo $425–$479/mo 6
Atlanta $149–$400/mo $249–$300/mo 6
Washington, DC $40–$449/mo $450–$549/mo 7
Miami $350/mo $300–$450/mo 5
Phoenix & Scottsdale $99–$199/mo $199–$299/mo 5
Seattle $299–$475/mo $179–$750/mo 10
Tampa $149–$550/mo $199–$800/mo 11
San Diego $89–$299/mo $189–$499/mo 7
Denver $99–$449/mo $199–$649/mo 10

Ranges show the lowest posted monthly price at each clinic, copied from clinic websites on October 27, 2026. Click a metro to see every clinic, what’s included and the source.

Brand-name vs. compounded

Many local clinics price “semaglutide” or “tirzepatide” without saying whether it is the FDA-approved brand or a compounded version. Compounded GLP-1s are not FDA-approved. Since the national shortages ended (tirzepatide in December 2024, semaglutide in February 2025), FDA has said pharmacies generally may not compound copies of these drugs, and in April 2026 it proposed further restrictions. Before you pay, ask any clinic: Which product is it, which pharmacy fills it, and is it the FDA-approved brand?

What drives the price

  • Brand vs. compounded (ask which one you’re getting).
  • Dose: self-pay prices rise with higher doses.
  • What’s bundled: visits, labs, body composition scans and coaching.
  • Coverage: employer insurance, Medicare’s $50 Bridge or Medicaid in some states.

Common questions

How much does Wegovy cost without insurance?

The Wegovy pen is $349 a month through NovoCare Pharmacy (new patients pay $199 for each of the first two fills of the starting doses through December 31, 2026). The Wegovy pill starts at $149 a month.

How much does Zepbound cost without insurance?

Through LillyDirect, Zepbound is $299 a month for 2.5 mg, $399 for 5 mg and $449 for 7.5–15 mg when you refill on time.

What is the cheapest GLP-1?

Among FDA-approved options, the Wegovy pill and Foundayo start at $149 a month self-pay. On Medicare, eligible patients pay $50 a fill through the GLP-1 Bridge.

Is compounded semaglutide legal?

Compounded GLP-1s are not FDA-approved. Since the shortages ended, FDA has said pharmacies generally may not compound copies of semaglutide or tirzepatide, with narrow exceptions. Ask any provider exactly which product you’d receive.

Prices were copied from each clinic’s own website on October 27, 2026 and are shown for comparison only; clinics change prices and promotions often, and what’s included varies. Confirm the current price, the exact medication and what’s included directly with the clinic. This page is not medical advice. Clinic owner? Update your price or listing.