GLP-1 Cost in Denver: Semaglutide & Tirzepatide Prices

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Quick answer: We checked 10 clinics in Denver that post their prices. Their lowest posted prices put semaglutide at $99–$449 a month and tirzepatide at $199–$649 a month (October 2026). Prices vary with what’s included (visits, labs, the medication itself) and whether it’s brand-name or compounded. Brand-name self-pay prices start at $149 a month (Wegovy pill, Foundayo), $299 (Zepbound) and $349 (Wegovy pen).

Posted GLP-1 prices at Denver clinics

Clinic Medication Price What’s included Source
Natura Med Spa & IV Bar
Aurora / Denver (Cherry Creek), CO · 720-513-5786
semaglutide $99/mo RN consultation + personalized plan + check-ins Posted price
Weight Loss MD - Cherry Creek
Denver (Cherry Creek), CO · (720) 279-1164
semaglutide $179 ongoing provider care + shipping; online or in office (period not stated on page) Posted price
Defiance Health
Centennial, CO · (719) 480-2400
semaglutide $200–$650/mo free consult, monitoring, dose adjustments, nutrition guidance; labs extra; brand and compounded offered Posted price
Laser Beauty Works
Denver (Highland), CO · (720) 315-6677
semaglutide $249/mo injections + monitoring; $75 consult credited to first treatment Posted price
Luxe Looks Med Spa
Denver, CO · (720) 557-0548
semaglutide compounded $275–$300/mo medication + monthly follow-up visits; $40 consult credited; labs required Posted price
Hellenic Laser Spa
Denver (Lowry), CO · 303-366-3222
semaglutide $275/mo not itemized; page says prices accurate as of June 2024 Posted price
Vivid Beauty Clinic
Northglenn, CO · (720) 461-1602
semaglutide $300–$600 weekly injections; monthly visit to collect shots Posted price
ZenVita Med Spa
Aurora, CO · (720) 224-8024
semaglutide $349/mo monthly medication program; 6-mo body-contouring bundles $7,999-$9,699 Posted price
The Luxe Room
Denver (RiNo), CO · (303) 222-9546
semaglutide $449/mo monthly provider follow-ups + free monthly body composition Posted price
Natura Med Spa & IV Bar
Aurora / Denver (Cherry Creek), CO · 720-513-5786
tirzepatide $199/mo consultation + customized plan Posted price
Weight Loss MD - Cherry Creek
Denver (Cherry Creek), CO · (720) 279-1164
tirzepatide $299 ongoing provider care + shipping (period not stated on page) Posted price
Defiance Health
Centennial, CO · (719) 480-2400
tirzepatide $350–$950/mo starting $350/mo; maintenance $650-$950/mo per page table Posted price
Vivid Beauty Clinic
Northglenn, CO · (720) 461-1602
tirzepatide $399 personalized care plan Posted price
Luxe Looks Med Spa
Denver, CO · (720) 557-0548
tirzepatide compounded $400–$775/mo medication + monthly follow-up visits; price rises with dose Posted price
Hellenic Laser Spa
Denver (Lowry), CO · 303-366-3222
tirzepatide $425/mo not itemized; page says prices accurate as of June 2024 Posted price
ZenVita Med Spa
Aurora, CO · (720) 224-8024
tirzepatide $449/mo monthly medication program; 6-mo body-contouring bundles $8,499-$10,299 Posted price
Laser Beauty Works
Denver (Highland), CO · (720) 315-6677
tirzepatide $449/mo injections + monitoring; $75 consult credited to first treatment Posted price
The Luxe Room
Denver (RiNo), CO · (303) 222-9546
tirzepatide $649/mo monthly provider follow-ups + free monthly body composition Posted price
Juventas Wellness
Denver, CO · 303-731-6585
program $250/mo GLP program: physician visit, monthly nurse check-ins, InBody scans; unclear if medication included Posted price

“Posted price” links to the page where each price appeared. Clinics without a public price aren’t shown here; see all GLP-1 clinics in Denver.

Brand-name self-pay prices (national)

Medication Self-pay price Where
Wegovy pill (oral semaglutide) $149/mo (1.5 mg); about $199–$299/mo for higher doses NovoCare Pharmacy, pharmacies
Wegovy pen (semaglutide) $199 for each of the first two fills (0.25 & 0.5 mg, new patients, through Dec 31, 2026), then $349/mo; Wegovy HD 7.2 mg $399/mo NovoCare Pharmacy
Zepbound (tirzepatide) $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg with on-time refills) LillyDirect
Foundayo (orforglipron pill) $149/mo (0.8 & 2.5 mg), $199 (5.5 mg), $299 (9–17.2 mg with on-time refills) LillyDirect
Medicare GLP-1 Bridge $50 per fill for eligible Part D enrollees (July 2026–Dec 2027) Medicare guide

Manufacturer self-pay prices as published by Novo Nordisk (NovoCare) and Eli Lilly (LillyDirect), checked October 27, 2026. Prices require a prescription and can change; some are limited-time offers.

Brand-name vs. compounded

Many local clinics price “semaglutide” or “tirzepatide” without saying whether it is the FDA-approved brand or a compounded version. Compounded GLP-1s are not FDA-approved. Since the national shortages ended (tirzepatide in December 2024, semaglutide in February 2025), FDA has said pharmacies generally may not compound copies of these drugs, and in April 2026 it proposed further restrictions. Before you pay, ask any clinic: Which product is it, which pharmacy fills it, and is it the FDA-approved brand?

Ways to pay less

  • Check insurance first: see does insurance cover GLP-1s.
  • On Medicare? The GLP-1 Bridge covers Wegovy, Foundayo and Zepbound KwikPen for $50 a fill if you qualify.
  • Compare total cost, not the headline: ask whether the price includes the medication, visits, labs and dose increases.
  • Measure results: a DEXA scan every 8–12 weeks shows whether you’re paying to lose fat or muscle.

Common questions

How much does semaglutide cost in Denver?

Among Denver clinics that post prices, the lowest posted semaglutide prices range from $99–$449 a month. Brand-name Wegovy costs $349 a month self-pay ($199 for the first two fills for new patients through 2026), and the Wegovy pill starts at $149.

How much does tirzepatide cost in Denver?

Among Denver clinics that post prices, the lowest posted tirzepatide prices range from $199–$649 a month. Brand-name Zepbound costs $299–$449 a month through LillyDirect.

Why are clinic prices so different?

Some prices include visits, labs and the medication; others are visit fees only, introductory first-month prices or per-injection prices. Some clinics use brand-name drugs and others compounded versions, which are not FDA-approved. Always ask what’s included.

Does insurance cover GLP-1s in Denver?

It depends on your plan. About a third of employers cover GLP-1s for weight loss, Medicare covers them for $50 through the GLP-1 Bridge if you qualify, and only some state Medicaid programs do. See our insurance guide.

Prices were copied from each clinic’s own website on October 27, 2026 and are shown for comparison only; clinics change prices and promotions often, and what’s included varies. Confirm the current price, the exact medication and what’s included directly with the clinic. This page is not medical advice. Clinic owner? Update your price or listing.