GLP-1 Cost in San Diego: Semaglutide & Tirzepatide Prices

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Quick answer: We checked 7 clinics in San Diego that post their prices. Their lowest posted prices put semaglutide at $89–$299 a month and tirzepatide at $189–$499 a month (October 2026). Prices vary with what’s included (visits, labs, the medication itself) and whether it’s brand-name or compounded. Brand-name self-pay prices start at $149 a month (Wegovy pill, Foundayo), $299 (Zepbound) and $349 (Wegovy pen).

Posted GLP-1 prices at San Diego clinics

Clinic Medication Price What’s included Source
Vedanu Wellness
San Diego, CA · (858) 222-2883
semaglutide $89/mo new-patient promo: first month $89, second month free (Level 1; valid to 10-31-2026) Posted price
Dermacare Medical Aesthetics
San Diego (Rancho Bernardo), CA · 858-487-3376
semaglutide compounded $200–$450/mo compounded semaglutide, may include B12 or L-carnitine Posted price
Daydream MD
San Diego, CA · 619.391.2390
semaglutide $215–$315/mo medication shipped every 28 days + monthly check-ins + dosing support; shipping included Posted price
Encinitas Weight Loss
Encinitas, CA · 760-943-1300
semaglutide $229/mo free consult + monthly in-person provider guidance + unlimited dose adjustments; flat rate all doses Posted price
Uniquely Fit Medical Weight Loss
Chula Vista, CA · (619) 552-2050
semaglutide $299–$499/mo membership; obesity-medicine consult + body comp report + plan; $299 first-month special Posted price
Vedanu Wellness
San Diego, CA · (858) 222-2883
tirzepatide $189/mo new-patient promo: first month $189, second month free (Level 1; valid to 10-31-2026) Posted price
Daydream MD
San Diego, CA · 619.391.2390
tirzepatide $290–$490/mo medication shipped every 28 days + monthly check-ins + dosing support; shipping included Posted price
Encinitas Weight Loss
Encinitas, CA · 760-943-1300
tirzepatide $379/mo free consult + monthly in-person provider guidance + unlimited dose adjustments; flat rate all doses Posted price
Uniquely Fit Medical Weight Loss
Chula Vista, CA · (619) 552-2050
tirzepatide $499–$699/mo membership; $499 first-month special Posted price
EmpowerMed Clinic
San Diego, CA · (619) 332-1806
semaglutide or tirzepatide $379/mo medication + monitoring + monthly provider consult + body comp scan; $249 labs/initial visit extra Posted price
Better Off
Encinitas, CA · 760-452-2722
program $400 program medical consultation + evaluation + personalized plan; medication extra Posted price
Dermacare Medical Aesthetics
San Diego (Rancho Bernardo), CA · 858-487-3376
program compounded $450–$600/mo compounded semaglutide + monitoring + support Posted price

“Posted price” links to the page where each price appeared. Clinics without a public price aren’t shown here; see all GLP-1 clinics in San Diego.

Brand-name self-pay prices (national)

Medication Self-pay price Where
Wegovy pill (oral semaglutide) $149/mo (1.5 mg); about $199–$299/mo for higher doses NovoCare Pharmacy, pharmacies
Wegovy pen (semaglutide) $199 for each of the first two fills (0.25 & 0.5 mg, new patients, through Dec 31, 2026), then $349/mo; Wegovy HD 7.2 mg $399/mo NovoCare Pharmacy
Zepbound (tirzepatide) $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg with on-time refills) LillyDirect
Foundayo (orforglipron pill) $149/mo (0.8 & 2.5 mg), $199 (5.5 mg), $299 (9–17.2 mg with on-time refills) LillyDirect
Medicare GLP-1 Bridge $50 per fill for eligible Part D enrollees (July 2026–Dec 2027) Medicare guide

Manufacturer self-pay prices as published by Novo Nordisk (NovoCare) and Eli Lilly (LillyDirect), checked October 27, 2026. Prices require a prescription and can change; some are limited-time offers.

Brand-name vs. compounded

Many local clinics price “semaglutide” or “tirzepatide” without saying whether it is the FDA-approved brand or a compounded version. Compounded GLP-1s are not FDA-approved. Since the national shortages ended (tirzepatide in December 2024, semaglutide in February 2025), FDA has said pharmacies generally may not compound copies of these drugs, and in April 2026 it proposed further restrictions. Before you pay, ask any clinic: Which product is it, which pharmacy fills it, and is it the FDA-approved brand?

Ways to pay less

  • Check insurance first: see does insurance cover GLP-1s.
  • On Medicare? The GLP-1 Bridge covers Wegovy, Foundayo and Zepbound KwikPen for $50 a fill if you qualify.
  • Compare total cost, not the headline: ask whether the price includes the medication, visits, labs and dose increases.
  • Measure results: a DEXA scan every 8–12 weeks shows whether you’re paying to lose fat or muscle.

Common questions

How much does semaglutide cost in San Diego?

Among San Diego clinics that post prices, the lowest posted semaglutide prices range from $89–$299 a month. Brand-name Wegovy costs $349 a month self-pay ($199 for the first two fills for new patients through 2026), and the Wegovy pill starts at $149.

How much does tirzepatide cost in San Diego?

Among San Diego clinics that post prices, the lowest posted tirzepatide prices range from $189–$499 a month. Brand-name Zepbound costs $299–$449 a month through LillyDirect.

Why are clinic prices so different?

Some prices include visits, labs and the medication; others are visit fees only, introductory first-month prices or per-injection prices. Some clinics use brand-name drugs and others compounded versions, which are not FDA-approved. Always ask what’s included.

Does insurance cover GLP-1s in San Diego?

It depends on your plan. About a third of employers cover GLP-1s for weight loss, Medicare covers them for $50 through the GLP-1 Bridge if you qualify, and only some state Medicaid programs do. See our insurance guide.

Prices were copied from each clinic’s own website on October 27, 2026 and are shown for comparison only; clinics change prices and promotions often, and what’s included varies. Confirm the current price, the exact medication and what’s included directly with the clinic. This page is not medical advice. Clinic owner? Update your price or listing.