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GLP-1 Cost in Chicago: Semaglutide & Tirzepatide Prices

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Quick answer: We checked 6 clinics in Chicago that post their prices. Their lowest posted prices put semaglutide at $150–$350 a month and tirzepatide at $225–$409 a month (October 2026). Prices vary with what’s included (visits, labs, the medication itself) and whether it’s brand-name or compounded. Brand-name self-pay prices start at $149 a month (Wegovy pill, Foundayo), $299 (Zepbound) and $349 (Wegovy pen).
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Posted GLP-1 prices at Chicago clinics

Clinic Medication Price What’s included Source
Zorah Medical
Des Plaines, IL · (708) 412-4040 		semaglutide $110/week weekly injection + physician oversight; 3-month program $949 (consult, labs, 12 injections, B12) Posted price
Way Less Clinic
Oak Brook, IL · (630) 230-5152 		semaglutide $150–$299/mo 4-week supply only; $150 intro first 2 months; $99/mo membership lowers price Posted price
Naperville Health & Wellness Clinic
Naperville, IL · (877) 885-8784 		semaglutide $249–$300/mo weekly injections + 3D body scans + medical supervision; labs extra Posted price
PURE Medical Spa
Chicago (Gold Coast), IL · (312) 312-7873 		semaglutide $299/mo monthly subscription (inclusions not itemized) Posted price
Innovative MedSpa
Chicago (Lincoln Park / River North), IL · (773) 420-8571 		semaglutide compounded $350/mo medication + monthly provider visit (self-pay) Posted price
Way Less Clinic
Oak Brook, IL · (630) 230-5152 		tirzepatide $225–$350/mo 4-week supply only; membership pricing $225–$325 Posted price
Innovative MedSpa
Chicago (Lincoln Park / River North), IL · (773) 420-8571 		Zepbound brand $399–$549/mo self-pay medication via Lilly Direct; follow-up visits billed to insurance Posted price
Naperville Health & Wellness Clinic
Naperville, IL · (877) 885-8784 		tirzepatide $409–$459/mo weekly injections + 3D body scans + medical supervision; labs extra Posted price
Chicago Concierge Weight Loss
Niles, IL · 847.696.9900 		program $399/mo core GLP-1 program incl. semaglutide or tirzepatide; hormone add-on from $599/mo Posted price

“Posted price” links to the page where each price appeared. Clinics without a public price aren’t shown here; see all GLP-1 clinics in Chicago.

Brand-name self-pay prices (national)

Medication Self-pay price Where
Wegovy pill (oral semaglutide) $149/mo (1.5 mg); about $199–$299/mo for higher doses NovoCare Pharmacy, pharmacies
Wegovy pen (semaglutide) $199 for each of the first two fills (0.25 & 0.5 mg, new patients, through Dec 31, 2026), then $349/mo; Wegovy HD 7.2 mg $399/mo NovoCare Pharmacy
Zepbound (tirzepatide) $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg with on-time refills) LillyDirect
Foundayo (orforglipron pill) $149/mo (0.8 & 2.5 mg), $199 (5.5 mg), $299 (9–17.2 mg with on-time refills) LillyDirect
Medicare GLP-1 Bridge $50 per fill for eligible Part D enrollees (July 2026–Dec 2027) Medicare guide

Manufacturer self-pay prices as published by Novo Nordisk (NovoCare) and Eli Lilly (LillyDirect), checked October 27, 2026. Prices require a prescription and can change; some are limited-time offers.

Brand-name vs. compounded

Many local clinics price “semaglutide” or “tirzepatide” without saying whether it is the FDA-approved brand or a compounded version. Compounded GLP-1s are not FDA-approved. Since the national shortages ended (tirzepatide in December 2024, semaglutide in February 2025), FDA has said pharmacies generally may not compound copies of these drugs, and in April 2026 it proposed further restrictions. Before you pay, ask any clinic: Which product is it, which pharmacy fills it, and is it the FDA-approved brand?

Ways to pay less

  • Check insurance first: see does insurance cover GLP-1s.
  • On Medicare? The GLP-1 Bridge covers Wegovy, Foundayo and Zepbound KwikPen for $50 a fill if you qualify.
  • Compare total cost, not the headline: ask whether the price includes the medication, visits, labs and dose increases.
  • Measure results: a DEXA scan every 8–12 weeks shows whether you’re paying to lose fat or muscle.
Know what you’re losingBook a DEXA scan to measure fat vs. muscle before you start.Start online with a physicianZyndio reviews your DEXA results before anything is prescribed.Find a GLP-1 clinic near youCompare clinics in all 50 states.

Common questions

How much does semaglutide cost in Chicago?

Among Chicago clinics that post prices, the lowest posted semaglutide prices range from $150–$350 a month. Brand-name Wegovy costs $349 a month self-pay ($199 for the first two fills for new patients through 2026), and the Wegovy pill starts at $149.

How much does tirzepatide cost in Chicago?

Among Chicago clinics that post prices, the lowest posted tirzepatide prices range from $225–$409 a month. Brand-name Zepbound costs $299–$449 a month through LillyDirect.

Why are clinic prices so different?

Some prices include visits, labs and the medication; others are visit fees only, introductory first-month prices or per-injection prices. Some clinics use brand-name drugs and others compounded versions, which are not FDA-approved. Always ask what’s included.

Does insurance cover GLP-1s in Chicago?

It depends on your plan. About a third of employers cover GLP-1s for weight loss, Medicare covers them for $50 through the GLP-1 Bridge if you qualify, and only some state Medicaid programs do. See our insurance guide.

Prices were copied from each clinic’s own website on October 27, 2026 and are shown for comparison only; clinics change prices and promotions often, and what’s included varies. Confirm the current price, the exact medication and what’s included directly with the clinic. This page is not medical advice. Clinic owner? Update your price or listing.