Home › GLP-1 clinics › GLP-1 Dose Schedule
| Medication | Doses in order | Time per step |
|---|---|---|
| Zepbound (tirzepatide) weekly injection | 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg | 4 weeks |
| Wegovy (semaglutide) weekly injection | 0.25 mg → 0.5 mg → 1 mg → 1.7 mg → 2.4 mg | 4 weeks |
| Wegovy pill (oral semaglutide) daily | 1.5 mg → 4 mg → 9 mg → 25 mg | about 30 days |
| Foundayo (orforglipron) daily pill | 0.8 mg → 2.5 mg → 5.5 mg → 9 mg → 14.5 mg → 17.2 mg | about 30 days |
Schedules reflect the manufacturers’ prescribing information and patient materials. Doses are increased gradually to reduce nausea and other stomach side effects; your prescriber decides when, and whether, to move up.
Starting low and increasing every few weeks gives your stomach time to adjust and reduces nausea, vomiting and other side effects. The starting doses are not meant to produce full weight loss.
Yes. Many people reach their goals on a lower maintenance dose. Zepbound maintenance doses are 5, 10 or 15 mg, and Foundayo doses above 5.5 mg are optional. Your prescriber decides based on your results and side effects.
Follow the instructions that came with your medication or call your pharmacist, because the rules differ between weekly injections and daily pills. If you miss several doses, your prescriber may restart you at a lower dose.
This tool is for general education only. It is not medical advice and cannot tell you whether a medication is right for you. Results vary widely from person to person. Talk with a licensed clinician before starting, stopping or changing any medication. Last reviewed October 27, 2026.